Non-Flagellar Type III Secretion Systems (NF-T3SS, or injectisomes) are bacterial machineries partially homologous to the bacterial flagellum, which allow direct injection of bacterial effectors from bacterial cytoplasm to eukaryotic cells via a molecular needle (cf. schema above). NF-T3SS are found in animal and plant pathogens (Yersinia pestis,Escherichia coli, Burkholderia,...), but also in plant and insect symbionts (e.g., Rhizobiales).
This website allows to query a dataset of 216 NF-T3SS retrieved from 1385 complete genome sequences. These systems were detected with proteic profiles of NF-T3SS core genes (sctC, sctN, sctJ, sctQ, sctR, sctS, sctT, sctU, sctV), and with an analysis of the genomic context of the hits obtained. This dataset along with the methodology is described in Abby and Rocha 2012.
Proteic profiles used for this study are available to analyze user data on the Mobyle web server: http://mobyle.pasteur.fr/cgi-bin/portal.py#forms::T3SSscan-FLAGscan. These profiles allow to detect both NF-T3SS and flagella.